Aug 23, - Retinoid creams or lotions can help clear your skin and also lessen wrinkles. Products made with sulfur can be good for the occasional spot treatment. Benzoyl peroxide is another acne fighter. Use benzoyl peroxide products only occasionally, because they can dry out your skin, Day says. Read about acne treatment, home remedies, medication side effects, and learn what causes and what prevents pimples. Plus, get information on how to get rid.